Cape Coral is best reached via the Southwest Florida International Airport (RSW) of Fort Myers, 30 km away.
Furthermore, Cape Coral is also well connected via the more remote international airports of Miami and Tampa. Within about 2.5 hours drive via the comfortable American highways you will reach Cape Coral relaxed.
With the following links you can get a detailed description.
Note:
From Ft.Myers and Miami, Cape Coral can be reached via one of the two chargeable bridges over the Caloosahatchee River. The fee is only charged for the passage to Cape Coral..
When traveling via Miami, tolls of approx. $ 3 USD
each direction in cash to pay and Tampa bridge fees are due for driving over the Tampa Bay.